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Tag · 3 articles

mTOR

Concurrent Training Molecular Interference: AMPK vs mTOR Truth
research·10 min read

Concurrent Training Molecular Interference: AMPK vs mTOR Truth

Running cuts hypertrophy gains 39% via AMPK-mTOR interference; cycling only 11%. See the 6-hour separation rule that keeps both intact.

concurrent training·AMPK·mTOR
Mechanical Tension: The Primary Driver of Hypertrophy?
research·9 min read

Mechanical Tension: The Primary Driver of Hypertrophy?

mTOR signaling, mechanotransduction, titin — mechanical tension touches all three growth pathways. Here is what the evidence says it actually drives.

mechanical·tension·hypertrophy
Concurrent Training Interference Effect: What the Research Actually Shows
research·6 min read

Concurrent Training Interference Effect: What the Research Actually Shows

Mixing cardio and lifting isn't automatically counterproductive, but the interference effect is real for some goals. Here's its size and how to avoid it.

concurrent training·interference effect·AMPK